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sinemet facts from trusted sources:
The maximum concentration of levodopa after a single dose of Sinemet CR was about 35% of the standard SINEMET (Carbidopa-Levodopa) (1151 vs. Sinemet CR 25-100 is available to facilitate titration and as an alternative to the half-tablet of Sinemet CR 50-200. Therefore, when therapy with Sinemet CR is started, dosage adjustment of the antihypertensive drug may be required. Therefore, caution should be exercised when Sinemet CR is administered to a nursing woman. However, global ratings of improvement as assessed by both patient and physician were better during therapy with Sinemet CR than with SINEMET (Carbidopa-Levodopa). It is important that Sinemet CR be taken at regular intervals according to the schedule outlined by the physician.
sinemet information at Drugs.com
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